spatially resolved metabolomics profiling (MetWare Ltd)
Structured Review

Spatially Resolved Metabolomics Profiling, supplied by MetWare Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spatially resolved metabolomics profiling/product/MetWare Ltd
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism"
Article Title: The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism
Journal: Advanced Science
doi: 10.1002/advs.202411980
Figure Legend Snippet: Spatial metabolomics profiled shows that TZP reduced glycolysis in the colon cancer tissues. A) Illustration of colonic and peritumoral tissues used for spatial metabolomic datasets. B) Examples of the microscopy‐mass spectrometry imaging (MSI) overlay. MSI images of D‐glucose (m/z = 249.1235) and H&E images of CRC tissue sections. Scale bar: 50 µm C) Heatmap of glycolysis‐related metabolites across all experimental animals of both groups. Red represented higher levels and blue, lower levels. D) Region‐specific MS images of CRC tissue sections. E) Violin plotting to show data distribution and its probability density; the thin black line extending from it, the 95% confidence interval; the black horizontal line in the middle, the median; and the outer shape, the distribution density of the data ( n = 3). Statistical significance was determined by unpaired t‐test and p values were adjusted with the t unpaired test comparisons test.
Techniques Used: Microscopy, Mass Spectrometry, Imaging